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Sir Shankar Balasubramanian FRS (born 30 September 1966) is an Indian-born British chemist and Herchel Smith Professor of Medicinal Chemistry in the Department of Chemistry the University of Cambridge, Senior Group Leader at the Cancer Research UK Cambridge Institute and Fellow of Trinity College, Cambridge. He is recognised for his contributions in the field of nucleic acids. He is scientific founder of Solexa and Cambridge Epigenetix.


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Education

Born in Madras (now Chennai) India in 1966, Shankar Balasubramanian moved to the UK with his parents in 1967. He grew up in a rural area just outside Runcorn in Cheshire and attended Daresbury Primary School, then Appleton Hall High School (which has since amalgamated to form Bridgewater High School). He then went on to study at Fitzwilliam College, Cambridge, where he did his undergraduate degree in Natural Sciences (1985-88) and continued with a PhD for research on the Reaction mechanism of the enzyme Chorismate synthase supervised by Chris Abell (1988-1991).


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Career

Following his PhD, Balasubramanian travelled to the USA as a SERC/NATO Research Fellow and worked in the group of Professor Steven J Benkovic at Pennsylvania State University (1991-1993). He started his independent academic career in 1994 in the University of Cambridge and has remained there ever since, first as College Lecturer, then University Lecturer (1998), University Reader in Chemical Biology (2003) and Professor of Chemical Biology (2007). He was most recently appointed Herchel Smith Professor of Medicinal Chemistry in 2008. He currently directs research laboratories in the Department of Chemistry and also the CRUK Cambridge Institute at the Cambridge Biomedical Campus.


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Research

Balasubramanian works in the field of nucleic acids.

More recently Balasubramanian has been inventing and applying new chemical methods to study epigenetic changes to DNA bases including single base resolution sequencing of 5-formylcytosine, 5-hydroxymethylcytosine and 5-methylcytosine.


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Honours and Awards

  • 1998 Glaxo Wellcome Award for Innovative Organic Chemistry
  • 2002 Corday-Morgan Medal and Prize of the Royal Society of Chemistry
  • 2009 Royal Society Mullard Award
  • 2010 BBSRC Innovator of the Year
  • 2010 BBSRC Commercial Innovator of the Year
  • 2011 Elected Fellow of the Academy of Medical Sciences (FMedSci)
  • 2012 Elected Fellow of the Royal Society (FRS)
  • 2012 Elected member of EMBO
  • 2013 Tetrahedron Prize
  • 2014 Biochemical Society Heatley Medal and Prize

Balasubramanian was knighted in the 2017 New Year Honours for services to science and medicine.

Source of the article : Wikipedia



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